Question: What Is Kleine Levin Syndrome?

How long does Kleine Levin syndrome last?

Individuals with Kleine-Levin syndrome may have episodes that last for a few days or up to several weeks.

Episodes occur approximately two to 12 times per year.

Most affected individuals exhibit no symptoms of Kleine-Levin syndrome between episodes..

What illnesses make you sleepy all the time?

But other illnesses can also leave you feeling washed out.What’s the difference between tiredness and fatigue? We all experience tiredness at times, which can be relieved by sleep and rest. … Anaemia. … Sleep apnoea. … Underactive thyroid. … Coeliac disease. … Chronic fatigue syndrome. … Diabetes. … Glandular fever.More items…

What does KLS stand for?

KLSAcronymDefinitionKLSKey Largo School (Florida)KLSKuala Lumpur Sentral (commercial and transportation area; Malaysia)KLSKaba Lodging Systems (global electronic lock provider)KLSKleine-Levine Syndrome (neurological disorder)15 more rows

What is Klein’s disease?

Klein’s Syndrome, also known as Waardenburg Syndrome, is a rare genetic disorder that is characterized by deafness, defects in structures arising from the neural crest, nose deformities and skin, iris and hair pigmentation abnormalities.

How rare is KLS?

SPECT has shown thalamic hypoperfusion of patients during episodes. KLS is very rare, occurring at a rate of 1 in 1 million, which limits research into genetic factors. The condition primarily affects adolescent males, though females can also be affected and the age of onset varies.

What mimics narcolepsy?

Beware: there are other diseases that can mimic narcolepsy: Obstructive sleep apnea (OSA) is the most common disorder in the category of sleep-related breathing disorders. Obstructive sleep apnea patients present with chronic excessive daytime sleepiness and are commonly misdiagnosed with narcolepsy.

Why do I sleep for days at a time?

Hypersomnia is a condition in which people have excessive daytime sleepiness. This means they feel tired during the day. Hypersomnia can also include situations in which a person needs to sleep a lot. This may be due to other medical conditions, but can also be due to a problem in the brain.

How is KLS diagnosed?

As a result, potential KLS patients often will undergo a lot of tests in various specialties: for metabolic problems including diabetes, metabolic encephalopathies and hypothyroidism; an MRI to rule out a lesion, tumor or inflammation as the cause; even for multiple sclerosis, which has aspects that can mimic the …

How is KLS similar to narcolepsy?

KLS is another disorder characterized by excessive sleepiness, but with different characteristics as compared to narcolepsy. KLS is characterized by extremely long sleep periods or prolonged night-time sleep.

Is there a cure for Kleine Levin Syndrome?

There is no definitive treatment for Kleine-Levin syndrome and watchful waiting at home, rather than pharmacotherapy, is most often advised. Stimulant pills, including amphetamines, methylphenidate, and modafinil, are used to treat sleepiness but may increase irritability and will not improve cognitive abnormalities.

Is KLS genetic?

The cause of this disease is unknown, but likely involves a major gene. KLS may be disproportionately frequent in the Jewish population, as the largest case series has been reported in this country, accounting for nearly one sixth of all patients reported worldwide.

Why would someone sleep for days?

Not getting enough sleep — sometimes by choice — is the most common cause of excessive sleepiness. Working at night and sleeping during the day is another. Other causes include drug, alcohol, or cigarette use, lack of physical activity, obesity, and the use of certain medications.

What causes KLS?

The exact cause of KLS is unknown, but some doctors believe certain factors can increase your risk for this condition. For example, KLS may arise from an injury in the hypothalamus, the part of the brain that controls sleep, appetite, and body temperature.

What is the rarest sleep disorder?

Kleine-Levin Syndrome (KLS), also known as “Sleeping Beauty” syndrome, is a rare neurological disorder characterised by recurrent bouts of hypersomnolence (excessive sleeping) along with cognitive and behavioural problems during wakefulness.

Why do I keep falling asleep when I’m not tired?

The most common causes of excessive sleepiness are sleep deprivation and disorders like sleep apnea and insomnia. Depression and other psychiatric problems, certain medications, and medical conditions affecting the brain and body can cause daytime drowsiness as well.